Methyl Sulfonyl Methane-MSM Supplements, Health Benefits & Side Effects

MSM (Methylsulfonylmethane)
   We usually take enough sulphur to ourselves through the food we eat. However, in some situations, it may be useful to add additional sulphur in the form of MSM. Especially in the case of known sulphur deficiency as well as various diseases of the musculoskeletal system ( Rheumatism, Arthritis , Osteoarthritis) or even special stresses and the use of Methylsulfonylmethane can lead to a noticeable improvement of the discomfort we experience.

Sulfur : Its Valuable Ingredient and its importance to your Body
    Sulfur is a chemical element and a vital mineral. Sulphur is involved in many metabolic pathways in practically all living organisms and is therefore extremely important for your physical well-being.

    Sulphur and its compounds are found in man and have numerous functions. The sulphur is absorbed in the form of sulfides and sulphates and can be converted into organic sulfur compounds. These organic sulphur compounds are then absorbed through your food metabolism.

   Sulphur is part of the only sulphurous and at the same time, essential amino acid methionine as well as the non-essential amino acids cysteine, cystine and homocysteine. Essential means that your body is not able to produce this amino acid itself. This must therefore necessarily be absorbed in sufficient quantities with the food. Thus, sulfur is also automatically part of all peptides and proteins containing the amino acid methionine.

    In addition, sulphur is part of cofactors biotin (vitamin B7, vitamin H), phosphate (vitamin B6) and coenzyme A. These cofactors are involved in numerous bodily biochemical processes and are therefore indispensable for the smooth functioning of these metabolic pathways.

    The amino acid, cysteine is easily oxidized to cystine. These bonds, among other things, contribute to the stabilization of protein structures, such as keratins. Keratins are the main ingredient of hair, feathers, toe fingernails, hooves, claws and horns, as well as beaks and similar structures. The keratin in the Horn of horses contains up to 5% sulfur.

    Sulfur is also part of the heparin involved in blood clotting and the chondroitin involved in cartilage tissue. The total sulphur content of the human body is approximately 0.25%, whereas the tissue species are different in their sulphur. In the oxygen-transporting Globinen, for example, the sulphur content in humans is 0.6%. All these metabolic processes in which sulphur is involved also show clearly that this is a really vital element.

    Sulphur has been used by humans for thousands of years. As early as 5000 BC, the Egyptians and Chinese used it as a bleaching agent for textiles, as a disinfectant and a medicinal product. The treatment of bacterial eye inflammation with sulphur is already described in the Papyrus boar.

In ancient Greece, sulphur was used as a disinfectant for the prevention of infectious diseases and for the sulfurisation of wine. Sulphur powder forms on the skin among other things bacteriostatic sulphides. Also, a fungicide (fungus-killing) and parasite-killing effect is known.

Previously, it was used in the form of ointments and creams, also for the treatment of acne and fungal infections (mycoses) of the skin. It is listed in the European Pharmacopoeia for external application and one of the fourteen homeopathic basic substances.

    Good sulphur sources of our daily food include: nuts and seeds, milk and dairy products, cheese, legumes, meat, eggs, cabbage, onions and garlic.

What is MSM?
MSM (Methylsulfonylmethane or Dimethylsulfon) is an organic sulfur compound which consists of about one-third of sulphur and is able to supply your body effectively with the important mineral sulfur. MSM naturally occurs in the human, animal and plant organism and, due to its good properties, among other things, it's a well-suited dietary supplement for the treatment of pain conditions.

MSM is formed in the organism from DMSO (dimethyl). DMSO is an already well-researched and approved medicinal product and is usually applied in the form of gels and ointments to the skin, as it can penetrate very well into the skin and penetrate the place of inflammation or pain.

DMSO acts as anti-inflammatory, analgesic, decongestant (for example, in bruises etc.) and vascular problem. However, DMSO is in higher concentration when ingesting over lungs, skin or swallowing, and is therefore only applied in a lower concentration.

Here, MSM is the ideal solution to this problem: it has the numerous positive effects of DMSO without having its side effects. MSM is also completely non-toxic in large quantities and can be easily fed orally in the form of MSM powder or as a tablet or capsule.


    Among other things, MSM has a pain relieving effect. The effects of MSM probably go back to four factors: inhibition of inflammation, relaxation of muscles, expansion of vessels and antioxidant properties. Methylsulfonylmethane is therefore often used as a nutritional supplement to support the treatment of musculoskeletal disorders (arthritis and osteoarthritis, among others).

    In this case, the combination of MSM with glucosamine (e.g. in the form of preparations containing Green-Lipped Mussel ) and chondroitin or the addition of vitamins and other minerals may also be useful.

    In animals, MSM is also used primarily for the treatment of joint ailments. Horses for example are often given MSM for the treatment of fur and hoof problems.

Application Areas of MSM
    The supply of MSM is recommended among other things:

  • Sulphur deficiency
  • Unbalanced diet
  • Joint ailments (e.g. arthritis, osteoarthritis)
  • Rheumatism, fibromyalgia, carpal tunnel syndrome
  • Muscle aches and cramps
  • Sports Injuries 
  • Brittle Nails and hair
  • For pain relief
  • To inhibit inflammation
  • Allergies, hay fever

    A positive support for many other complaints is discussed:
Sprains, strains, ligament injuries, herniated disc problems, tennis elbows, inflammation of the mucus bags and tendons, muscle cramps and pains,  circulatory disorders, back pain, headaches and migraines, scarring pain, digestive problems, chronic constipation, infections with Helicobacter pylori and heartburn.

  Also, skin damage, burns, ulcers, neurodermatitis, edema, candida fungal infections, parasites and worms, diabetes, (chronic) exhaustion and fatigue,  premenstrual syndrome, autoimmune diseases, Alzheimer's , ADS (ADHD), multiple sclerosis, cystic fibrosis, ulcerative, anti-inflammatory in acute infections , shortness of breath, bronchitis, asthma, snuff, bacterial infections, radical scavengers and many more.

It is also used to improve the following conditions:
    Relaxation of hardened muscles, increase in blood circulation, stimulation of cartilage build-up, relief from gout ailments, strengthening of mucous membranes (gastric tract, urinary tract), accelerated and improved wound healing, gastritis, prevention of colds, autoimmune reactions, strengthening of connective tissue, supports collagen construction, reduction of wrinkle formation.

    It is also used to improve skin elasticity, slow aging process of skin, acne, dry skin , eczema, varicose veins, for connective tissue weakness, hair loss, hair and nails strengthening, brittle hair and nails, dull hair, promotion of hair growth, bladder inflammation, improved mineral supply, reduction of Homocystein level.

Studies on MSM
    Several studies have already shown the positive influence of MSM on the symptoms of osteoarthritis. For example, in the study of the researchers of the Working Group around P. R. Usha of the Department of Clinical Pharmacology and therapy at the's Institute of Medical Sciences in Hyderabad, India, 2004; found that a daily gift of 500 mg MSM or 500 mg MSM plus 500 mg glucosamine could improve symptoms such as pain, swelling and the overall functioning of the joints.

   The 118 subjects of the placebo, in randomized double blind study were given either 3 x daily 500 mg MSM, 500 mg MSM plus glucosamine or a placebo for a period of 12 weeks. Particularly, good results could be achieved with the combination of MSM plus glucosamine.

    At the University of Memphis, Tennessee in the United States, the team at D. S. Kalman 2012 has focused on the effect of MSM on regeneration after sports. Eight men were investigated, who were given 1.5 or 3 grams of MSM daily for 28 days and were active for up to 150 minutes a week. It was found that, in particular, in a daily intake of 3 grams of MSM, various markers such as muscular hangover, fatigue and the status of antioxidants in the blood had a positive influence on daily, with intensive sports activities.

    At the Aging Research Center of the Korea Research Institute for Bioscience and Biotechnology in Daejeon (South Korea), 2014, J. H. Kim dealt with the effect of MSM on three cell lines of liver tumors as well as on tumor tissues of transgenic mice. They could show that MSM, depending on the dosage, was able to reduce tumor growth significantly.

    In the transgenic mice, the tumor development could be partly prevented. MSM treatment resulted in a reduced tumor size as well as a reduced tumor count. The results suggest that MSM has Anticancer effects on the studied liver cancer types.

    However, the numerous research groups agree that further studies must follow in order to further explore the potential of MSM.

Dosage forms and ingestion of MSM
Methylsulfonylmethane (MSM) can be easily taken for over a long period of time and is poor in side effects. It is available for ingestion in the form of tablets, capsules or as powder as well as for external use as gel. Its Powder form offers the advantage of the best dosing ability – tailored to individual needs.

   Capsules, in turn, are ideal for people who do not like MSM's own taste. MSM is available in pharmacies and rugstores as well as in numerous online shops. Pay attention to methylsulfonylmethane with the highest degree of purity. It is irrelevant whether you buy MSM of biological origin or synthetically produced MSM.

 The higher the percentage of the degree of purity (maximum 100%), the higher the purity and thus the quality. MSM products are usually free of animal ingredients, lactose (milk sugar), gluten, starch, preservatives, dyes, other auxiliary materials, as well as artificial aromas and flavouring agents. Special MSM products are also available for use in horses, dogs and cats.

Conclusion
    As numerous studies have shown, MSM has a soothing effect, particularly on inflammatory diseases of the locomotor system such as osteoarthritis and rheumatism. The sulphur, which is valuable and involved in countless biochemical reactions in the body, has an anti-inflammatory effect and alleviates pain.

 Man, horse, dog and cat benefit from this. Also, being in various dosage forms as tablet, capsule, powder as well as gel and the possibility to provide the body with almost no additional sulfur is another advantage.

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